Investigation on Antibacterial Activity of Carica Papaya Leaf Extracts against Wound Infection-Causing Bacteria

Nowadays, there is an increased sustained interest in the production of plant-based-drugs for the treatment of many diseases. Moreover, people are welcoming traditional medicines to overcome mild/serious illness. Due to increase in the thrust for the production of plant-based antimicrobials, the present study was performed on Carica papaya leaves. The leaf extract was prepared by using acetone, methanol, and water. The antimicrobial nature of the extract was studied by agar well diffusion method against wound infection-causing pathogens viz., Escherichia coli, Staphylococcus aureus, Proteus vulgaris, Klebsiella pneumoniae, and Pseudomonas aeruginosa. The acetone leaf extracts exerted pronounced antibacterial effect on gram negative bacteria especially Pseudomonas sp. The study revealed that papaya leaves could contain active antimicrobial compounds which may hinder the growth of wound infectioncausing pathogens in invitro conditions. The results obviously justified the importance of topical application of papaya leaf extracts to treat the wound infection as a traditional practice.